On: April 22, 2021 In: Blog Comments: 0


Injectable dermal fillers are gel-like substances that are injected underneath your skin to change its appearance. They’re a popular and minimally invasive treatment for wrinkles.

According to the American Board of Cosmetic Surgery, over 1 million people get injectable dermal fillers every year.

As you age, skin that sags or wrinkles can be caused by loss of fat and proteins in the skin layer. Injectables can’t permanently replace lost fat and proteins, but they can mimic your skin’s original structure.

Unlike  Botulinum Toxin treatments, which relax your muscles to minimize the appearance of wrinkles, dermal fillers are known for plumping up, adding volume or fullness, and smoothing your skin.


There are several categories of wrinkle fillers, and each works in a slightly different way.




Hyaluronic acid is already naturally produced by your skin. You may recognize the ingredient from cosmetics that claim to plump and hydrate your skin.

Hyaluronic acid fillers are gel-like, and results can last 6 to 12 months. These fillers tend to be a bit more expensive than collagen.

Brand names:









 Where you can use them 

Different types of fillers are recommended depending on the area of your body that you’re looking to target.

Deep wrinkles

While most of the fillers can be used for this area, there are a few that might be preferred by some people. These might include PMMA, polylactic acid, and certain hyaluronic acids.

Filler: ReplengenChaeum

Under-eye area

Fat injections, hyaluronic acid, and polylactic acid can be used around the eye area. Certain hyaluronic acids might be better than others for this area. Some tend to not provide the optimal correction, and can leave the area looking lumpy or bumpy.

You should be advised that no filler has been approved by the Food and Drug Administration (FDA) for use in the under-eye area.

Nasolabial or smile lines

Most of the hyaluronic acids and PMMA microspheres have been approved by the FDA for use in this area. They can be used for the smile lines and folds around your nose.

Forehead and crow’s feet

If you’re opposed to  Botulinum Toxin injections, filler solutions for your forehead furrows and crow’s feet include polylactic acid, calcium hydroxylapatite, and PMMA.

Fillers in this area are also not approved by the FDA, and many providers won’t use injectables in this area due to complications.

Filler: Elravie, Metoo


Cheeks can be plumped and structured with polylactic acid and many of the hyaluronic acids.


Most of the hyaluronic acids can be used as lip fillers, and they’ve been approved by the FDA to do so. Most of the other filler options shouldn’t be used on the lips.

Filler: Dermalax, Revolax


Calcium hydroxylapatite, hyaluronic acid, or essentially any of the above dermal fillers can be used to contour and add volume to the chin.

Filler: Rejeunesse, Bellast, Metoo


Hyaluronic acid and calcium hydroxylapatite can be used to fill in loose skin on your hands, as well as decrease the appearance of veins.

Chest or décolletage

Not to be confused with breast augmentation, wrinkles around your chest area and lower neck can be treated with hyaluronic acid.


Fillers do have measurable cosmetic benefits for your appearance. People who swear by fillers report younger-looking skin, fewer fine lines and wrinkles, and a more visible bone structure.

For those who are self-conscious about the visible signs of aging, fillers are fairly straightforward and work for their intended purpose.

Hyaluronic acid, in particular, may softenTrusted Source scar tissue and add volume to where it’s injected.


 Side effects 

Side effects of fillers are typically minimal and easy to manage. Frequently reported symptoms include:

  • swelling at the injection site
  • bruising
  • itching
  • pain in the days after treatment

In less common instances, you may experience rarer side effects. These side effects may be more likelyTrusted Source if you use hyaluronic acid or autologous fat injections as your filler material. Rare side effects include:

  • visible clumping of the filler material
  • filler material in an area of your face where it wasn’t injected, also called filler migration
  • headache
  • blurred vision and, in severe cases, blindness
  • allergic reaction
  • infection
  • discoloration or a change in skin pigment


Fillers may have a similar result to neurotoxin injections, more commonly known as the brand name Botulax, by giving you a more youthful appearance, but they work much differently.

Botulax works by paralyzing the muscle underneath your skin. It’s hard to know how each person’s body will react to  Botulinum Toxin, and how stiff the facial expressions might be afterward.

Botulax also takes days or weeks to settle, so the results aren’t immediately apparent. Results last 3 to 4 months.

With fillers, the material is injected underneath your skin. Depending on the type, this material might serve several purposes, but all fillers have the same aim: restoring lost volume to make skin look smoother, plumper, and more structured.

You can usually tell how fillers are working in the hours after treatment. Their results tend to last longer than Botulax — anywhere from 6 months to forever, depending on the type of filler material.



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